The worst rout in College Football history to-date was a game played in 1916 between Georgia Tech and Cumberland College.

Cumberland was already down 28-0 when they felt their defense was playing better than their offense.  They decided to kick off instead of receive the ball, hoping that the defense would pin Tech deep in its own end.

Well, that backfired, Georgia Tech returned the kick-off 70 yards to the Cumberland 10, scored again, and went on to defeat Cumberland an amazing 222-0!